New D-dimer Pair Recommendations

Published: 30.11.2021

Elevated levels of D-dimer have been found in the blood of patients with pulmonary embolism (PE) and deep vein thrombosis (DVT). The elevated level of D-dimer in blood is believed to be a reliable marker of pathological coagulation.

Our scientist has discovered new pairs for D-dimer immunoassay development for both chemiluminescence and lateral flow platforms. The new recommended pair for CLIA and LF-platform are described in Table 1.

Table 1. New pair recommendations for chemiluminescence and lateral flow platforms.

The new pairs are showing good correlation (R = 0.969) with commercially available D-dimer assay (Figure 1).
Figure 1. Correlation study of HyTest pair DD3cc (capture) and DD46cc (detection) with commercially available D-dimer assay. Clinical sample amount in the study was 65 and the correlation to commercially available D-dimer assay is r = 0.974.

Learn more:
D-dimer TechNotes
Cat# 4D30: D-dimer antibody
Cat# 8D70: D-dimer antigen 


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