S100 proteins are synthesized in astroglial cells and can be used as sensitive and reliable markers for central nervous system damage.
S100 proteins MAbs
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S100 proteins constitute a family of calcium-binding proteins. In brain
tissue, S100 proteins are represented mainly by the S100BB homodimer and
S100A1B heterodimer. Due to their abundance in the astrocytes of the
brain, S100 proteins are important neuro biomarkers, such as for glial
injury and blood-brain barrier damage. They have shown elevated results
over the first few days after severe traumatic brain injury (TBI).
At HyTest, we offer a selection of monoclonal antibodies and native S100 antigens that can be used in S100 assay development for brain injuries.
Cat# 4S37: S100 proteins, Human, antibody