Inflammation is body’s response to physical, biological, or chemical irritants. These include tissue injuries, burns and infections by microbes but also pathological situations that lead to atherosclerosis or ischemia, for example. The inflammatory reaction is protective and tightly regulated. Its purpose is to eliminate the cause of inflammation, get rid of dead cells and to initiate tissue repair.
Inflammation can be both acute and chronic. Acute inflammation occurs instantly as a response to inflammation stimuli and the signs are often prominent like redness of the skin or swelling. In contrast, the onset of chronic inflammation is slower, and the local signs may be much more subtle which makes the diagnosis more difficult.
At HyTest we provide immunological reagents — antibodies and antigens — that allow the development of quantitative immunoassays for detecting various inflammatory markers. These include C-reactive protein which is a non-specific marker of inflammation, procalcitonin which is useful when diagnosing sepsis and a selection of inflammatory mediators like interleukins and interferons.